Cleveland Clinic uses new AI model to find drug targets for the brain
GenT flags disease-linked genes for conditions like Alzheimer's, ALS, depression, and schizophrenia by cross-referencing genetic variants with multi-omics data. Researchers validated one concrete lead in the lab, not just on a screen: the NTRK1 gene in Alzheimer's tau pathology. That matters because drug target discovery remains neuro's biggest bottleneck, well ahead of clinical trials.
practitioners › Published in Nature Communications on May 11, 2026, alongside two framework extensions, MuGenT and xGenT.
Cleveland Clinic / Nature Communications →